Just so genome stories: what does my neighbor tell me?

Just so genome stories: what does my neighbor tell me?

Discovery supposes either chance or inductive reasoning. We document here an approach to explore genome texts, where the neighborhoods of genes and gene products (in the genome, in phylogeny, in metabolic pathways, in codon usage bias, ‘‘in biblio’’. . .) were used to make inferences about the function of unknown genes. Examples are provided in the case of pyrimidine biosynthesis, showing that ...

"So, Tell Me What Users Want, What They Really, Really Want!"

Equating users' true needs and desires with behavioural measures of 'engagement' is problematic. However, good metrics of 'true preferences' are difficult to define, as cognitive biases make people's preferences change with context and exhibit inconsistencies over time. Yet, HCI research often glosses over the philosophical and theoretical depth of what it means to infer what users really want....

What my cancer taught me.

Tell me a story...what can paediatricians gain from reading stories?

In our first article we considered literature for and about children, and how writing for the young has changed, reflecting different and evolving perspectives on childhood. In this second article, we will be asking whether literature can be used creatively and usefully in the training of doctors. The suggestion for the topic arose from a session we organised for paediatricians in the Communica...

This Is My (Post) Truth, Tell Me Yours

This is a commentary on the article 'The rise of post-truth populism in pluralist liberal democracies: challenges for health policy.' It critically examines two of its key concepts: populism and 'post truth.' This commentary argues that there are different types of populism, with unclear links to impacts, and that in some ways, 'post-truth' has resonances with arguments advanced in the period a...